Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism.

By C. Rowe, U. Ackerman, W. Browne, R. Mulligan, K. Pike, G. O'Keefe, H. Tochon-Danguy, G. Chan, S. Berlangieri, Gareth Jones and 14 more. Lancet Neurology, 2008

655 citations recorded by the source corpus.

Subfields: Physiology, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/24abfdf6337f12b6ee3cea9ff49c55ba7ecb40ae

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Citations in the corpus

β-Amyloid accumulation in the human brain after one night of sleep deprivation (2018, background): “There are several validated PET radiotracers for this purpose, including (18)Fflorbetaben (FBB) (22, 23).”
Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. (2018, background): “…bind amyloid (C11PiB [Klunk et al. 2004; Ikonomovic et al. 2008], F18-florbetapir [Wong et al. 2010; Clark et al. 2011, 2012], F18-flutemetamol [Vandenberghe et al. 2010; Wolk et al. 2011], and F18-florbetaben [Rowe et al. 2008]) can noninvasively assess if amyloid plaques are present in vivo.”
Brain imaging in Alzheimer disease. (2012, result): “At the time of writing, there have been one or two, small published studies using each of the fluorine-18-labelled tracers, [F-18]florbetaben (18F-BAY94-9172 or AV-1; Rowe et al. 2008), [F-18]florbetapir (AV-45; Wong et al. 2010; Clark et al. 2011) and [F-18]flu- temetamol (3 0 F-PiB or GE-067; Neli”
In Vivo Imaging of Amyloid Deposition in Alzheimer’s Disease using the Novel Radioligand [18F]AV-45 (Florbetapir F 18) (2010, background): “In contrast, other 18F-labeled Ab imaging agents appear not to reach asymptote until 90 min or more after administration (9,10).”