Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options.

By S. Srivastava, K. Ramana, Aruni Bhatnagar. 2005

540 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Physiology, Natural Language Processing

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Glaucius Oliva
2. L. Ferreira
3. Ricardo N Dos Santos
4. Adriano Defini Andricopulo
5. C. Kevil
6. S. Bir
7. G. Kolluru

Citations in the corpus

• Molecular Docking and Structure-Based Drug Design Strategies (2015, background): “Hyperglycemia induces overexpression of ALR2, leading to an increase in sorbitol concentration, which ultimately causes osmotic imbalance, alterations in membrane permeability, oxidative stress, and finally tissue damage [218].”
• Endothelial Dysfunction and Diabetes: Effects on Angiogenesis, Vascular Remodeling, and Wound Healing (2012, background): “Likewise, inhibitors of AR have proved to be effective for therapeutic intervention in diabetes [213].”