IFN-γ production by antigen-presenting cells: mechanisms emerge

By D. M. Frucht, T. Fukao, C. Bogdan, H. Schindler, J. O’Shea, S. Koyasu. 2001

471 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/23fce1d42a9c445fed152e0144c306e0645b9aac

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In Immunology

1. C. Bogdan
2. Sylvia M. Lee
3. K. Margolin

Citations in the corpus

• Nitric oxide and the immune response (2001, background): “IL-12 (with IL-18) induces iNOS in various populations of macrophages, through a mechanism mediated by autocrine production of IFN-&gamma”
• Cytokines in Cancer Immunotherapy (2011, background): “IFN- is secreted by NK cells, NKT cells, Th1 CD4+ T-cells, CD8+ T cells, antigen presenting cells (APCs) and B-cells [55,56].”
• PI3K-mediated negative feedback regulation of IL-12 production in DCs (2002, background): “In addition, IL-12 can induce macrophages and DCs to produce IFN-γ, which is a potent inducer of IL-12 and suggests the presence of a positive autocrine loop for the activation of APCs in the early phase of innate immunit”