Randomised trials in surgery: problems and possible solutions

By P. Mcculloch, I. Taylor, M. Sasako, B. Lovett, D. Griffin. British medical journal, 2002

756 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. (2008, background): “Eligibility criteria should be justified, because they will influence the applicability of the trial results (58, 73, 74).”
Surgical data science – from concepts toward clinical translation (2020, background): “Furthermore, randomized controlled trials (RCTs) to evaluate surgical interventions are difficult to perform (McCulloch et al., 2002).”
Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better? (2020, background): “In clinical research, RCT is not always feasible [35]; therefore, non-randomized design remains considerable.”
The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta‐analysis, and clinical practice guideline: a systematic review (2015, background): “In clinical research, especially in surgery, RCT is not always feasible (25).”