Polysaccharide colloidal particles as delivery systems for macromolecules.

By Kevin A. Janes, P. Calvo, M. J. Alonso. Advanced Drug Delivery Reviews, 2001

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Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging (2009, background): “3 Chitosan—Chitosan is a cationic, hydrophlilic polymer that is also nontoxic, biocompatible, and bioabsorbable, which has made it a popular material for drug delivery applications in recent years [169,170].”
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues (2008, background): “Chitosanbased or chitosan-coated nanoparticles represent another common group of mucoadhesive systems [124,125,141], and several groups have studied nanoparticles made of these polymers to deliver proteins [142,143], peptides [144], and DNA [145] to mucosal tissues.”
Hydrogel nanoparticles in drug delivery. (2008, background): “These studies demonstrated the feasibility of synthesizing stable, reproducible nanosized chitosan particles which could entrap and deliver drugs [155].”
In vitro cytotoxicity of nanoparticles in mammalian germline stem cells. (2005, background): “In particular, nanoparticles are now used to target synthetic peptides, proteins, oligonucleotides, and plasmids to specific cell type while protecting these macromolecules from enzymatic degradation (Chavany et al., 1994; Janes et al., 2001).”