TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

By M. Decressac, B. Mattsson, P. Weikop, M. Lundblad, Johan Jakobsson, A. Björklund. Proceedings of the National Academy of Sciences of the United States of America, 2013

702 citations recorded by the source corpus.

Subfields: Epidemiology, Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/2243fe6ea3fbae807f2d422d11b81a68a86b90cd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Andrea Ballabio
2. V. Deretic

In Physiology

1. G. Napolitano
2. Andrea Ballabio

Citations in the corpus

• Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities. (2017, unknown): “For example, many studies have demonstrated the protective effect of autophagy upregulation on α-synuclein toxicity (eg Decressac et al., 2013, Hebron et al., 2014, Spencer et al., 2009).”
• TFEB at a glance (2016, background): “…or pharmacological activation of TFEB in cellular and mouse models of Parkinson’s disease has been found to improve lysosomal function and ameliorate α-synuclein aggregation (Decressac et al., 2013; Dehay et al., 2010; Kilpatrick et al., 2015), which is a major hallmark of Parkinson’s disease.”