Chitin Induces Natural Competence in Vibrio cholerae

By K. Meibom, Melanie Blokesch, N. Dolganov, Cheng-Yen Wu, G. Schoolnik. Science, 2005

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Horizontal Gene Exchange in Environmental Microbiota (2011, background): “…conditions may also enhance HGT. Vibrio cholera, for example, can acquire new genetic material by natural transformation during growth on chitin, which activates regulatory cascades leading to increased cell density, nutrient limitation, and decline in growth rate and stress (Meibom et al., 2005).”
Water Microbiology. Bacterial Pathogens and Water (2010, background): “This process was demonstrated in vitro in cell suspensions and in vivo in the gut of the rat [8,13,19,20].”
Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline (2007, background): “cholerae (45), and tfoX expression is essential for this competence.”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “the aquatic environment (Stewart and Sinigalliano, 1990; Meibom et al., 2005; Baharoglu et al., 2012).”
Bacterial Quorum-Sensing Network Architectures (2009, neutral): “cholerae cells in the presence of chitin, which is believed to be important for serogroup conversion (6, 7, 73).”