Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition.
By M. Vickers, B. Breier, W. Cutfield, P. Hofman, Peter D. Gluckman. American Journal of Physiology. Endocrinology and Metabolism, 2000
1,019 citations recorded by the source corpus.
Subfields: Obstetrics and Gynecology, Pediatrics, Perinatology and Child Health, Physiology
View Paper: https://www.semanticscholar.org/paper/1fe7a5dcca7b20beff6a7942172297c0f3492a12
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In Obstetrics and Gynecology
In Pediatrics, Perinatology and Child Health
In Physiology
Citations in the corpus
- Neonatal leptin treatment reverses developmental programming. (2005, background): “It is notable in the present study in females that the programmed phenotype is expressed only in the presence of a high-fat diet postnatally, whereas we have previously shown in the male that programming can manifest independently of postnatal nutrition (9).”
- Early life events and their consequences for later disease: A life history and evolutionary perspective (2007, background): “In rats subjected to maternal undernutrition during pregnancy, the offspring develop a perturbed metabolic phenotype showing obesity, hyperphagia,hyperinsulinemia,andreducedactivity in open field testing, particularly if they are fed a high-fat diet after weaning (Vickers et al., 2000, 2003).”
- The Pathophysiology of Gestational Diabetes Mellitus (2018, background): “While potentially beneficial in times of famine, a mismatch between nutritional status in the womb and nutritional status once born can contribute to the development of obesity and metabolic disease [53,54].”
- Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 (2025, neutral): “57,58 This pattern of life-course exposure to the double burden of malnutrition triggers a metabolic capacity–load mismatch, which aggravates the risk of NCDs. 59 Furthermore, obesity exacerbates individuals’ susceptibility to infectious diseases and increases the risk of associated metabolic…”