THE EFFECT OF DIAZINON ON HAEMATOLOGICAL INDICES OF COMMON CARP (Cyprinus carpio L.)

By M. Svoboda, V. Lusková, J. Drastichová, V. Žlábek. 2001

188 citations recorded by the source corpus.

Svoboda M., V. Luskova, J. Drastichova, V. Ilabek: The Effect of Diazinon on Haematological Indices of Common Carp (Cyprinus carpio L). Acta Vet. Brno 2001, 70: 457-465. The goal was to assess an effect of diazinon [0,0-diethyl 0-(2-isopropyl-6-methylpyrimidin-4yl) phosphorothioate] on common carp (Cyprinus carpio L.). The effect was assessed based on results of acute toxicity tests and on a comparison of results of haematological examination of a control and an experimental group exposed to Basudin 600 EW pesticide preparation (active substance 600 g.l -1 of diazinon). The acute toxicity test lasting 96 h was performed semistatically on common carp juveniles. Examination of erythrocyte and leukocyte profile was performed on 15 control and 25 experimental specimens of one-to-two-year-old common carp after 96 h of exposure to Basudin 600 EW in concentration of 32.5 mg.l -1 . The 96hLC50 value of Basudin 600 EW for common carp juveniles was 26.7 mg.l-1. The experimental group of one- to two-year-old common carp showed significantly lower values (p < 0.01) of erythrocyte count (RBC), haemoglobin content (Hb) and haematocrit (PCV) compared to the control group. Values of MCV, MCH and MCHC were comparable in both groups during the study. In contrary, there was a significant decrease in leukocyte count (Leuko) (p < 0.01), as well as in both the relative and absolute lymphocyte count (p < 0.01) and a significant increase in both the relative and absolute count of developmental forms of neutrophile granulocytes: myelocytes (p < 0.01) and metamyelocytes (p < 0.05) in the experimental group. Relative and absolute count of monocytes and both the band- and segmented neutrophile granulocytes was comparable in both groups during the study. The diazinon-based Basudin 600 EW pesticide preparation was classified among harmful substances for fish. Changes in values of both the erythrocyte and leukocyte profile after exposure to diazinon-based preparation may be refered to disruption of haematopoiesis as well as to a decrease on non-specific immunity of the fish.

Subfields: Aquatic Science, Health, Toxicology and Mutagenesis, Immunology

View Paper: https://www.semanticscholar.org/paper/1f9831a599b2b2e5c38b561c0d359be28b59423f

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In Aquatic Science

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In Health, Toxicology and Mutagenesis

Citations in the corpus

Effects of diazinon on blood parameters in the African catfish (Clarias gariepinus). (2009, methodology): “…effect of various pesticides on the behaviors and haematological responses of various species of fish, (Anees, 1978; Benarji and Rajendranath, 1990; Svoboda et al., 2001) and have found varying responses after exposing the fish to varying sublethal concentrations using the 96 h acute toxicity…”
Effect of sub-lethal Diazinon Concentrations on Blood Plasma Biochemistry (2008, background): “Alteration in values of MCV, MCH and MCHC in Cyprinus carpio (Svoboda et al., 2001) was reported.”
Ecotoxicology: a review of pesticides induced toxicity in fish. (2015, background): “, 2012) and Cyprinus carpio (Svoboda et al., 2001) in response to Diazinon, Mystus keletius to methyl parathion (Sampath et al.”
The effect of diazinon on blood plasma biochemistry in carp (Cyprinus carpio) (2002, background): “…603 65 Brno, Czech Republic Phone: +420 5 4342 2527 Fax: +420 5 4321 1346 E-mail: luskova@brno.cas.cz http://www.vfu.cz/acta-vet/actavet.htm The present paper is a sequel to an earlier contribution devoted to the effect of diazinon on the haematological indices in common carp (Svoboda et al. 2001).”