Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations

By I. Patel, T. Seemungal, M. Wilks, S. Lloyd-Owen, G. Donaldson, J. Wedzicha. Thorax, 2002

739 citations recorded by the source corpus.

Subfields: Emergency Medical Services, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/1e9493bccf9d74684ecbe1cc15d28449707a8db8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Emergency Medical Services

1. P. Barnes

In Pulmonary and Respiratory Medicine

1. P. Barnes
2. J. Wedzicha
3. T. Seemungal
4. G. Donaldson
5. John R. Hurst
6. T. Wilkinson
7. D. Parums

Citations in the corpus

• Mediators of Chronic Obstructive Pulmonary Disease (2004, background): “There is a correlation between IL-8 concentrations and the bacterial colony count in sputum, indicating that bacterial infection may induce neutrophilic inflammation, at least in part, via induction of IL-8 release in the airways (Hill et al., 2000; Patel et al., 2002).”
• Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. (2004, background): “Exacerbations are heterogeneous in etiology and in the nature of presenting symptoms (22, 29 ).”
• How cigarette smoke skews immune responses to promote infection, lung disease and cancer (2009, background): “and to microbial colonization of the airways, which occurs in approximately a third of patients with COP”