Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China

By Y. Guan, B. Zheng, Y. He, X. L. Liu, Z. Zhuang, C. Cheung, S. Luo, Philip H. Li, L. J. Zhang, K. Butt and 7 more. Science, 2003

2,284 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/1e6a25cb1d49fefd81cf2af3e7e2771558d73cba

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In Animal Science and Zoology

In Infectious Diseases

Citations in the corpus

Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study (2020, background): “Detection of SARS-CoV in Himalyan palm civets and horseshoe bats identified 29 nucleotide sequences that helped trace the origins of SARS-CoV isolates in humans to these intermediary species [13, 24, 38, 77].”
Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses (2016, background): “Regarding SARS-CoV, epidemiology data implicated masked palm civets (Paguma larvata) from live animal markets (LAM) in Guangdong Province, China, as a route of exposure to SARS-CoV [46].”
SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat (2020, background): “For example, masked palm civet and dromedary camels are the intermediate hosts for SARS-CoV [49] and MERS-CoV respectively [60].”
The Molecular Biology of Coronaviruses (2006, background): “Isolates of SARS-CoV from marketplace animals near the source of the epidemic were found to contain an additional 29 nucleotides absent from all but one previously reported human isolate, and this apparent insertion resulted in the fusion of ORFs 8a and 8b into a single ORF 8 (Guan et al., 2003).”
Coronavirus Pathogenesis (2011, background): “Subsequent studies of wild caught animals in these markets detected evidence of SARS-CoV infection in Himalayan palm civets (Paguma larvata) and raccoon dogs (Nyctereutes procyonoides) suggesting these species as possible sources for human infections (Guan et al., 2003).”
Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia (2020, background): “For example, a partial deletion was detected in SARS coronavirus found in palm civets (6).”
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus (2020, positive): “Among coronaviruses, point mutations have been demonstrated to confer resistance to neutralizing antibodies in MERS-CoV (Tang et al., 2014) and SARS-CoV-1 (Sui et al., 2008; ter Meulen et al., 2006).”
Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS‐CoV) in SARS patients: implications for pathogenesis and virus transmission pathways (2004, neutral): “It has been demonstrated that SARS-associated coronavirus (SARS-CoV) is the primary causative pathogen of SARS [2–6] and may originate from some wild animals, such as Himalayan palm civets [7].”
SARS and MERS: recent insights into emerging coronaviruses (2016, positive): “The first indication of the source of SARS-CoV was the detection of the virus in masked palm civets and a raccoon dog and the detection of antibodies against the virus in Chinese ferret badgers in a live-animal market in Shenzhen, China 25 .”