Genetics of Lactase Persistence and Lactose Intolerance

By A. Rattray, J. Strathern, Ian R. Henderson. 2008

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The evolutionary significance of cis-regulatory mutations (2007, background): “An important recent human dietary adaptation is the ability to digest lactose as an adult, a condition known as lactase persistenc”
How culture shaped the human genome: bringing genetics and the human sciences together (2010, background): “Lactose tolerance is frequent in northern Europeans and in pastoralist populations from Africa and the Middle East, but is almost completely absent elsewhere; these differences relate to genetic variation near the lactase ( LCT ) gen”
Convergent adaptation of human lactase persistence in Africa and Europe (2006, background): “LPH is predominantly expressed in the small intestine, where it hydrolyzes lactose into glucose and galactose, sugars that are easily absorbed into the bloodstrea”
The Origins of Lactase Persistence in Europe (2009, methodology): “elsewhere in the world [1–4].”