Oligometastases revisited

By R. Weichselbaum, S. Hellman. Nature Reviews Clinical Oncology, 2011

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Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal (2018, positive): “’’ The spatial distribution of metastatic disease in ccRCC varies from solitary (a single metastasis in a single location), oligo (limited in number and location; usually defined as %5 or %3 metastases) (Weichselbaum and Hellman, 2011), and widespread (multiple metastases in multiple sites).”
Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study. (2019, methodology): “Eligible patients (1) had pathologically confirmed NSCLC, (2) had stage IV disease according to the seventh edition of the American Joint Committee on Cancer staging system, (3) had three or fewer metastases, not including the primary tumor, (4) had an Eastern Cooperative Oncology Group performance ”
Consolidative Radiotherapy for Limited Metastatic Non–Small-Cell Lung Cancer: A Phase 2 Randomized Clinical Trial (2018, background): “The median (range) number of maintenance chemotherapy cycles was 3 (115) for the maintenance-only group and 5 (3-19) for the SAbR group; individual patient treatment information is included in Tables 2 and 3.”