Inflammation after trauma: Microglial activation and traumatic brain injury
By Anil F. Ramlackhansingh, D. Brooks, R. Greenwood, S. Bose, Federico E. Turkheimer, Kirsi M. Kinnunen, S. Gentleman, Rolf A. Heckemann, Karen Gunanayagam, G. Gelosa and 1 more. Annals of Neurology, 2011
949 citations recorded by the source corpus.
Subfields: Molecular Biology, Neurology
View Paper: https://www.semanticscholar.org/paper/1cb217212d72721e1165ee20c5a617d77c92ae67
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
In Neurology
Citations in the corpus
- Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro (2013, methodology): “Inflammatory events influence the reactivity of glia in the brain long-term and any prior activation state of microglia is likely to alter the efficacy of immunomodulatory therapies (Nagamoto-Combs et al., 2007; Ramlackhansingh et al., 2011).”
- Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. (2012, neutral): “…in 10 patients studied more than 11 months after moderate to severe TBI reported significantly increased binding bilaterally at sites distant from areas of focal injury, such as thalamus, and correlated these changes with several measures of cognitive dysfunction (Ramlackhansingh et al., 2011).”
- Microglia in the TBI Brain: The Good, The Bad, And The Dysregulated (2015, background): “…TBI (Acosta et al., 2013; Aungst et al., 2014; Johnson et al., 2013; Loane et al., 2014a; Mouzon et al., 2014; Nagamoto-Combs et al., 2007; Nonaka et al., 1999; Ramlackhansingh et al., 2011; Smith et al., 2013), with limited capacity for tissue repair, particularly after moderate-to-severe TBI.”
- Inflammation and white matter degeneration persist for years after a single traumatic brain injury. (2013, background): “Interestingly, a recent study by Ramlackhansingh et al. (2011) failed to show increased microglial activation in the corpus callosum of long-term TBI survivors as assessed by PET imaging using the ligand [11C](R)PK11195 (PK).”