Oxidative stress and apoptosis: impact on cancer therapy.

By T. Ozben. Journal of Pharmacy and Science, 2007

727 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/1bcaba0c12925d30a84589c6693e0a2db692b7e5

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In Molecular Biology

1. Yu Chen
2. Longqin Hu
3. S. Magesh

Citations in the corpus

• Cisplatin in cancer therapy: molecular mechanisms of action (2014, unknown): “Excessive reactive oxygen species can induce apoptosis through both the extrinsic and intrinsic pathways (Ozben, 2007).”
• Apoptosis and cancer: mutations within caspase genes (2009, background): “Apoptosis induction might be achieved in several ways—for example, by promoting the expression of pro-apoptotic factors while reducing the expression of antiapoptotic factors only in the tumour cells, or by means of the infection of viral particles that act specifically within the transformed cells.”
• Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy (2012, unknown): “Both ROSelevating and ROS-eliminating strategies have been developed; the former have been predominantly used (134, 135, 237, 272).”
• Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment (2009, unknown): “Additionally, modulation of antioxidant systems has been adopted as a novel therapeutic approach; however, contra-dictory results have failed to clarify whether antioxidant mechanisms should be enhanced or inhibited during cancer treatment (84).”
• Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents (2012, background): “Curcumin has been shown to possess a number of therapeutic properties including antiinflammatory, antioxidative, antiarthritic, antiischemic, and anticarcinogenic effects and has been evaluated in clinical trials for various diseases including multiple myeloma, pancreatic cancer, colon cancer, psori”