The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt.

By C. Frank, M. Mohamed, G. Strickland, D. Lavanchy, R. Arthur, Laurence S. Magder, Taha El Khoby, Yehia Abdel-Wahab, El Said Aly Ohn, W. Anwar and 1 more. The Lancet, 2000

1,234 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/1b314df03ff421f92cde5d559c682d56a9e0c112

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

In Hepatology

Citations in the corpus

Smooth skyride through a rough skyline: Bayesian coalescent-based inference of population dynamics. (2008, background): “A gradual transition from the intravenous to oral administration of the PAT started in the 1970s (Frank et al. 2000).”
Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy (2023, background): “In 2015, approximately 6.3% of the population of Egypt was estimated to be infected with HCV, as a consequence of a mass anti-schistosomal therapy campaign between the 1950s and the 1980s in which unsterilized needles and syringes were used to administer tartar emetic 47,48 .”
Estimation of the global burden of disease attributable to contaminated sharps injuries among health-care workers. (2005, background): “HCV prevalence has reached alarming levels over recent decades in a number of countries of the Emr and Afr region [Khan et al., 2000; Frank et al., 2000; World Health Organization, 2000a].”
Global Distribution and Prevalence of Hepatitis C Virus Genotypes (2014, background): “The high prevalence and dominance of subtype 4a in Egypt is widely believed to have resulted from its spread by way of unsafe injections during past anti-schistosomal public health campaigns.(40) Other subtypes have been amplified locally and regionally after being introduced into networks of inject”
The immunobiology of schistosomiasis (2002, background): “Moreover, it now seems clear that in Egypt at least, where HCV and schistosomiasis are two of the most important public-health problems and have geographically overlapping distributions, the coincidence of infection is a result of the unfortunate initial widespread transmission of HCV by mass parent”
The global burden of hepatitis C (2009, background): “In Egypt, the treatment of endemic schistosomiasis in mass programmes (discontinued in the 1980s) that frequently used unsterilized needles and syringes has led to a national HCV prevalence of more than 14%, with rates of 20–30% in young male adults (19, 20).”
Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis (2014, background): “China 144,316 (85,432-232,946) 174,878 (115,884-222,366) 155,645 (119,644-196,756) 114,352 (77,031-197,745) Korea, Democratic People’s Republic 2,278 (1,293-3,782) 3,225 (1,900-5,190) 4,143 (2,421-6,707) 4,934 (2,851-7,929) Taiwan 3,723 (2,267-5,862) 4,984 (3,075-7,679) 5,598 (3,532-8,456) 6,243 (3,”
Genetic diversity and evolution of hepatitis C virus--15 years on. (2004, background): “For example, the current sequence diversity and phylogenetic tree structure of genotype 4a in Egypt is compatible with the introduction of HCV into that population through parenteral treatment for schistosomiasis (Bilharzia) (tragically, with non-disposable and poorly sterilized needles) in the 1950”