Mechanisms of use-dependent plasticity in the human motor cortex.

By C. Bütefisch, B. Davis, S. P. Wise, L. Sawaki, Leonid Kopylev, Joseph Classen, Leonardo G. Cohen. Proceedings of the National Academy of Sciences of the United States of America, 2000

647 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Neurology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/1ac9ff30d5d8e5ea412b623bdcbf1f84c48453fc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. John C. Rothwell
2. Leonardo G. Cohen
3. Hartwig Roman Siebner
4. Peter W. Kalivas
5. Alvaro Pascual-Leone
6. Jörn Diedrichsen
7. Randall Flanagan
8. C. O'Brien

In Neurology

1. John C. Rothwell
2. Leonardo G. Cohen
3. Hartwig Roman Siebner
4. Alvaro Pascual-Leone
5. Peter W. Kalivas
6. Steven C. Cramer
7. Helen S. Mayberg
8. Bruce H. Dobkin

In Rehabilitation

1. Steven C. Cramer
2. Alvaro Pascual-Leone
3. B. Kolb
4. Leonardo G. Cohen

Citations in the corpus

• Mechanisms of enhancement of human motor cortex excitability induced by interventional paired associative stimulation (2002, background): “This kind of cortical plasticity was prevented when training was performed under the influence of lorazepam, a drug that enhances GABAA receptor function (Bütefisch et al. 2000).”
• Harnessing neuroplasticity for clinical applications (2011, positive): “Indeed, many classes of drugs can retard neuroplasticity (Feeney et al., 1982; Butefisch et al., 2000) and possibly reduce behavioural gains (Goldstein and Sygen in Acute Stroke Study Investigators, 1995; Lazar et al.”
• Transcranial magnetic stimulation: new insights into representational cortical plasticity (2002, positive): “Premedication with dextromethorphan (a N-methyl-daspartate receptor blocker) and lorazepam (a positive allosteric modulator of GABA type-A receptors) substantially reduced use-dependent plasticity, indicating that Nmethyl-d-aspartate receptor activation and GABAergic inhibition may be involved (Bute”
• The Role of GABA in Human Motor Learning (2011, neutral): “There is considerable variability in motor learning behavior across individuals [7], and the present study aimed to test whether some of this variability could be explained by variation in responsiveness of the GABA system, because GABAmodulation plays an important role in learning [1–4].”
• Robotics, motor learning, and neurologic recovery. (2004, positive): “Other models have found that lorazepam and dextromethorphan impair use-dependent plasticity in motor cortex (7).”
• Rapid task-related plasticity of spectrotemporal receptive fields in primary auditory cortex (2003, background): “, unmask silent synapses, alter neuronal gain or change the level of excitabilit”
• Use-Dependent and Error-Based Learning of Motor Behaviors (2010, methodology): “The term use-dependent learning has been used in previous work (Classen et al., 1998; Bütefisch et al., 2000) to refer to neural or behavioral changes that are induced through the simple repetition of movements in the absence of systematic errors.”
• Principles of sensorimotor learning (2011, background): “This learning mechanism can be disrupted through GABA agonists 73 .”