Human sulfotransferases and their role in chemical metabolism.

By N. Gamage, A. Barnett, N. Hempel, R. Duggleby, K. Windmill, Jennifer L. Martin, M. McManus. Toxicological Sciences, 2006

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Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism (2009, background): “There are various human sulfotransferases (both cytosolic and membrane-bound), but human cytosolic sulfotransferase SULT1A1, which acts on acetaminophen, has a broad substrate range and is one of the most important sulfotransferases for xenobiotic sulfonation as well as acting on several endogenous ”
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats (2010, background): “The gastrointestinal tract, liver, and kidneys possess high levels of Phase II metabolizing activities [14, 39]; resveratrol has been reported to undergo rapid and extensive glucuronidation and sulfation, and the gastrointestinal tract may be the major site for its metabolism [13, 19].”