Mesenchymal stem cells: building blocks for molecular medicine in the 21st century.

By A. Caplan, S. Bruder. Trends in Molecular Medicine, 2001

1,137 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/19a61faaaa5ce964d359ccead3b2775971d609f7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. R. Lee
2. Andrea Augello
3. C. De Bari
4. A. Caplan
5. C. Gregory
6. J. Hubbell
7. L. Meirelles
8. Jeffrey L Spees

In Molecular Biology

1. Andrea Augello
2. C. De Bari
3. C. Gregory
4. J. Hubbell
5. A. Caplan
6. Jeffrey L Spees
7. M. Lutolf
8. R. Lee

In Rheumatology

1. Andrea Augello
2. C. De Bari
3. A. Caplan

Citations in the corpus

• Mechanisms of mesenchymal stem/stromal cell function (2016, background): “These observations sparked a substantial degree of interest in the potential application of MSCs for the repair of serious connective tissue trauma and disease [6–10].”
• Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005, background): “An increased understanding of the cellular and molecular foundations of tissue development and regeneration has paved the way towards more effective therapies for regenerative medicine and tissue engineerin”
• The Regulation of Differentiation in Mesenchymal Stem Cells (2010, positive): “These initial observations were then extended by the study of CFU-f proliferative abilities and phenotypic characteristics (Castro-Malaspina et al., 1980; Prockop, 1997; Caplan and Bruder, 2001).”
• Isolation of renal progenitor cells from adult human kidney. (2005, background): “37 However, the cells isolated from kidney were strongly and persistently positive for CD133, a marker that is usually lacking in mesenchymal stem cells.”
• Mechanisms involved in the therapeutic properties of mesenchymal stem cells. (2009, background): “The notion that BM contains MSCs has been and still is useful for the purpose of tissue engineering, which relies on the ability of these cells to differentiate into tissue-specific cell types when combined with biomaterials and given proper differentiation stimuli [9].”
• Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. (2005, background): “It has been suggested that MSCs are a main source of pericytes within the bone marrow stroma (11, 16, 17, 40, 43); thus, hMSCs may integrate into”