Mechanisms of multidrug resistance in cancer.
By J. Gillet, Michael M. Gottesman. Methods in molecular biology, 2010
690 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/195698a307046f6e478523a9f50c85dc4ffcb6db
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In Molecular Biology
In Oncology
Citations in the corpus
- Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes (2012, background): “…cassette transporter known for years as P-glycoprotein or MDR1, functions as a pump to efflux a variety of structurally unrelated anticancer drugs, leading to cellular resistance to re- lated substrates but not to cisplatin (Gottesman et al., 2002; Gottesman, 2002; Gillet and Gottesman, 2010).”
- The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade. (2015, background): “The mechanisms that cancer cells utilize or develop to evade chemotherapy are complex and have been described in detail in several recent reviews (Gillet and Gottesman, 2010; Gottesman et al., 2002; Szakacs et al., 2006).”