Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury.

By Mark A. LaBarge, Helen M. Blau. Cell, 2002

819 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/18cad120904648741dd81b769afec31a88bbc435

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Citations in the corpus

Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage (2012, background): “…in their proliferation rate, clonogenic capacity, extent and rate of differentiation, and ability to self-renew, these variations also exist between satellite cells of the same muscle (Day et al., 2010; Lagord et al., 1998; Molnar et al., 1996; Ono et al., 2010; Ono et al., 2012; Schultz, 1996).”
Muscle satellite cells adopt divergent fates (2004, background): “The most intriguing of these nonmuscle sources is bone marrow, which produces cells that are able to move into the satellite cell niche, arriving via the circulation following bone marrow grafts (Fukada et al., 2002; LaBarge and Blau, 2002), suggesting that this could also be a usual source of myoge”
Plasticity of marrow-derived stem cells. (2003, neutral): “5% of the muscle fibers in response to muscle damage with exercise.(46) Also, this study documents the progression from donor-derived uninucleate cells to multinucleate muscle cells, thereby demonstrating that the behavior of marrow derived myocytes is similar to that of normal muscle cells.”
The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, background): “It should be noted, however, that a large proportion of bone marrow-derived cells incorporating into myofibers do T h e Jo u rn al o f H is to ch em is tr y & C yt o ch em is tr y not actually activate the myogenic program (Lapidos et al. 2004; Wernig et al. 2005).”
Pax7 and myogenic progression in skeletal muscle satellite cells (2006, background): “It has been proposed that satellite cells may be part of a hierarchical system and merely represent a committed myogenic precursor that is restricted to providing myonuclei, where replacement of satellite cells occurs from a stem cell located within the muscle interstitum and/or outside muscle tissu”