Tandem Base Lesions Are Generated by Hydroxyl Radical within Isolated DNA in Aerated Aqueous Solution

By A. Bourdat, T. Douki, S. Frelon, and Didier Gasparutto, J. Cadet. 2000

108 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/17a4043f06bff96c64c02cd262cadb31a5dd5703

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In Molecular Biology

1. J. Wagner
2. J. Cadet

Citations in the corpus

• DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation. (2013, background): “…was shown that pyrimidine peroxyl radicals formed by oxidative reactions involving either †OH or one-electron oxidants are able to efficiently add to adjacent purine (Douki et al. 2002a) and pyrimidine bases (In et al. 2007), giving rise to tandem base lesions in isolated DNA (Bourdat et al. 2000).”