Activation of the human orbitofrontal cortex to a liquid food stimulus is correlated with its subjective pleasantness.

By Morten L. Kringelbach, John P. O'Doherty, E. T. Rolls, C. Andrews. Cerebral Cortex, 2003

855 citations recorded by the source corpus.

Subfields: Experimental and Cognitive Psychology, Nutrition and Dietetics, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/178e1b17918766c7d9c85cf3f9f02619c7fc41f8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Experimental and Cognitive Psychology

1. E. T. Rolls
2. Didier Grandjean
3. Kent C. Berridge
4. David Sander
5. Klaus R. Scherer
6. Morten L. Kringelbach
7. John P. O'Doherty
8. Antonio Rangel

In Nutrition and Dietetics

1. Kent C. Berridge
2. Morten L. Kringelbach
3. S. Peciña
4. Kyle S. Smith
5. John P. O'Doherty
6. S. Mahler
7. Jaak Panksepp
8. Jocelyn M. Richard

In Sensory Systems

1. Kent C. Berridge
2. Morten L. Kringelbach
3. E. T. Rolls
4. S. Peciña
5. John P. O'Doherty
6. Kyle S. Smith
7. S. Mahler
8. Jaak Panksepp

Citations in the corpus

• Hedonic Hotspots: Generating Sensory Pleasure in the Brain (2007, positive): “Orbitofrontal cortex activity in rats, monkeys and humans also tracks changes in pleasure of a constant food stimulus, or the alliesthetic reductions in hedonic impact caused by eating foods to satiety (Burke and Schoenbaum, this volume; Faurion et al., 1998; Hollerman et al., 2000; Kringelbach, thi”
• The rewards of music listening: Response and physiological connectivity of the mesolimbic system (2005, background): “The few extant studies of positive emotion have tended to use drugs of addiction to induce those positive emotions artificially (Berridge, 2003), and only recently have more naturalistic and ecologically valid studies of positive emotion been conducted (Kringelbach et al., 2003; Small et al., 2001).”
• The Representation of Information About Taste and Odor in the Orbitofrontal Cortex (2010, background): “A decrease in activation by the food eaten to satiety relative to the other food was found in the orbitofrontal cortex (Kringelbach et al. 2003), but not in the primary taste cortex.”
• Marketing actions can modulate neural representations of experienced pleasantness (2008, result): “The setup was similar to those used by previous studies in which liquid food had been administered (14).”
• Neural correlates of rapid reversal learning in a simple model of human social interaction (2003, result): “This is consistent with the role of the human orbitofrontal cortex in processing both primary rewards (e.g., Kringelbach et al., 2003) and more abstract rewards such as money (O'Doherty et al., 2001; Thut et al., 1997).”
• Emotion and attention interactions in social cognition: Brain regions involved in processing anger prosody (2005, positive): “(e.g., Anderson et al., 2003; Zald and Pardo, 1997), gustatory (e.g., Small et al., 2003; Kringelbach et al., 2003), touch-related (Rolls et al., 2003), and visual (e.g., Nitschke et al., 2004; Kawasaki et al., 2001) domains.”
• Identification of Human Gustatory Cortex by Activation Likelihood Estimation (2011, background): “…right hemisphere for pleasant stimuli, [Small et al., 2003; Zald and Pardo, 2000]), and (2) motivation to consume chemosensory stimuli (with activity in the medial and lateral OFC associated with increased and decreased motivation for consumption [Kringelbach et al., 2003; Small et al., 2001a]).”
• The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. (2010, background): “Similarly, taste reactivity studies in rats have shown that dopamine suppression by pimozide (dopamine antagonist) administration or even by massive destruction of 99% of mesolimbic and neostriatal dopamine neurons (by 6-OHDA lesions) does not suppress taste “liking” facial expressions elicited by…”
• Ever-changing cycles of musical pleasure: The role of dopamine and anticipation. (2012, background): “A similar satiety phase is found for other rewards (Gottfried, O’Doherty, & Dolan, 2003; Kringelbach et al., 2003), whereas few rewards, such as money and drugs that directly affect the dopamine systems, might lack a satiety phase completely (Kringelbach & Berridge, 2010).”
• Emotion and the Prefrontal Cortex: An Integrative Review (2017, result): “Numerous studies have found results consistent with this finding (Critchley & Rolls, 1996; Kringelbach et al., 2003; O'Doherty et al., 2000).”
• The neurobiology of positive emotions. (2006, background): “The orbital frontal cortex has been found to be activated in fMRI brain imaging of positive emotional states related to taste induced PA (Kringelbach et al., 2003) olfactory induced PA (Rolls et al.”