Inaugural Article: The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels

By D. Ko. 2003

216 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/17570ae119dced149750e08bb32111131852c220

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Michael S. Brown
2. J. Goldstein
3. H. Kwon
4. Lina Abi-Mosleh
5. Michael L. Wang
6. J. Deisenhofer
7. R. Infante
8. J. Malhotra

Citations in the corpus

• Structure of N-terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol (2009, background): “NPC2 was shown previously to bind with high affinity to cholesterol but not to cholesterol derivatives with hydrophilic substitutions on the isooctyl side chain, such as 25-hydroxycholesterol (25-HC) and 27-HC (Okamura et al., 1999; Friedland et al., 2003; Ko et al., 2003; Infante et al., 2008b).”