Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

By Manish M Patel, Roger I. Glass, Kenichiro Akazawa, Jan Vinjé, Umesh D. Parashar. Emerging Infectious Diseases, 2008

986 citations recorded by the source corpus.

Noroviruses accounted for 12% of severe gastroenteritis cases among children <5 years of age.

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Foodborne Illness Acquired in the United States—Major Pathogens (2011, positive): “For norovirus, we estimated the number of hospitalizations and deaths by applying the estimated proportion of acute gastroenteritis illnesses caused by norovirus to overall estimates of hospitalizations and deaths from acute gastroenteritis; this choice is supported by studies of hospitalizations fo”
Global Causes of Diarrheal Disease Mortality in Children <5 Years of Age: A Systematic Review (2013, methodology): “Patel et al [25] estimated 218 000 deaths due to norovirus among children under 5, but this was calculated using very different methods and assumptions: they used an attributable fraction due to norovirus when data on asymptomatic children was available, and applied their mean isolation rate of 12.1”
Foodborne Illness Acquired in the United States (2011, positive): “[30,31] For most other pathogens, we used data from surveillance to estimate pathogen-specific hospitalizations and deaths and doubled the numbers to adjust for underdiagnosis.”
Norovirus illness is a global problem: emergence and spread of norovirus GII.4 variants, 2001-2007. (2009, background): “!5 years old, it is critical that studies be conducted to assess the role played by NoVs in childhood diarrhea [8, 9].”