Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders

By P. Krakowiak, C. Walker, A. Bremer, Alice Baker, Sally Ozonoff, R. Hansen, I. Hertz-Picciotto. Pediatrics, 2012

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Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring (2016, positive): “Recent epidemiological evidence suggests that exposure to maternal obesity in utero increases the risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD) in children (Connolly et al., 2016; Krakowiak et al., 2012; Sullivan et al., 2014).”
The Changing Epidemiology of Autism Spectrum Disorders (2016, neutral): “, chronic inflammation, fetal hypoxia, oxidative stress, insulin resistance) (106, 118, 119, 187).”
The Central Nervous System and the Gut Microbiome (2016, background): “A recent report indicates that maternal diet may also change both the microbial population and behavior of offspring (Buffington et al., 2016), following clinical data showing an association between maternal obesity and an ASD diagnosis in children (Krakowiak et al., 2012).”