Dishevelled: The hub of Wnt signaling.

By Chan Gao, Ye-Guang Chen. Cellular Signalling, 2010

780 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/161f71da82c21d3c54431ea6d77efa8d10b4acf4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Michael A. Rudnicki
2. G. Schulte
3. Qingxiang Zeng
4. J. Petersen
5. Junjiang Liu
6. Jin Yang
7. J. Mu
8. Shuzhi Deng

In Molecular Biology

1. H. Yin
2. Feodor D. Price
3. Yanqin Zuo
4. Michael A. Rudnicki
5. G. Schulte
6. Qingxiang Zeng
7. J. Petersen
8. L. Yao

Citations in the corpus

• Targeting cancer stem cell pathways for cancer therapy (2020, background): “129, 130 Aberrant Wnt signaling is found in many cancers, such as invasive ductal breast carcinomas, 131 colorectal cancer, 132 papillary thyroid cancer, 133 esophageal cancer, 134 and colorectal cancer.”
• Wnt/β-catenin signaling in cancers and targeted therapies (2021, background): “Moreover, DIX mediated the polymerization of Dvl monomer, which assembles as the anchoring site for Axin and Gsk3β.(197) This process may have significant effects on the ligand–receptor/co-receptor internalization.”
• Satellite cells and the muscle stem cell niche. (2013, background): “The Wnt/PCP pathway is involved in planar cell polarization (PCP) and establishment of polarized cellular structures (183).”
• INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY REVIEW WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3 (2014, positive): “…at the crossroads of several FZD-induced pathways and plays not only an important role in the β-catenin-dependent but also in the independent signalling pathway, such as the WNT/β-catenin, the PCP pathway, the WNT/RAC, the WNT/RHO and possibly also the WNT/Ca2+ pathway (Gao and Chen, 2010).”
• Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway (2015, background): “A study has shown that ITCH degrades the phosphorylated form of disheveled (Dvl) via the proteasome pathway, thus inhibiting the action of the canonical Wnt pathway [13].”
• Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer (2021, background): “Through the binding of FZD receptors or ROR1/ROR2/RYK coreceptors, Wnt/RCP and Wnt/Ca signaling cascades are activated for transcriptional responses and/or cytoskeletal rearrangement.(184,185) In Wnt/β-catenin signaling, CAF-derived β-catenin became a major concern, as it is seemed to be a relativel”