Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating

By E. Perozo, A. Kloda, D. Cortes, B. Martinac. Nature Structural Biology, 2002

645 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Cryo-EM analysis of a membrane protein embedded in the liposome (2020, background): “The mechanosensitive channels are gated by the mechanical force in part exerted by the deformation of the membrane (9).”
Membranes are more mosaic than fluid (2005, background): “What effect the energy of distorting the bilayer might have on the protein itself is not known, but might have functional relevance for cases where the protein varies its transmembrane conformation in the course of activit”
How lipids affect the activities of integral membrane proteins. (2004, background): “coli (EcMscL) has been reconstituted into a series of phosphatidylcholines of different chain lengths [135].”