Drosophila Liprin-α and the Receptor Phosphatase Dlar Control Synapse Morphogenesis

By N. Kaufmann, Jamin DeProto, Ravi Ranjan, Hong Wan, D. V. Vactor. 2002

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LAR, liprin α and the regulation of active zone morphogenesis (2007, background): “…liprin α and LAR interactors Mint1 MALS/Veli LAR Liprin α Jo ur na l o f C el l S ci en ce 3725LAR, liprin and active zones both LAR and liprin mutant larvae have enlarged active zones, 2.5 and 2.4 times the size of wild-type active zones, respectively (Kaufmann et al., 2002).”
GFP Reconstitution Across Synaptic Partners (GRASP) defines cell contacts and synapses in living nervous systems. (2008, background): “PTP-3A and related proteins affect synaptic development and morphology in C. elegans, Drosophila, and vertebrates (Ackley et al., 2005; Dunah et al., 2005; Kaufmann et al., 2002).”
Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting (2003, background): “Mutations in both Dliprin-␣ and Dlar (Drosophila homologs of liprin-␣ and LAR) lead to defects in axon terminal branching and active zone dimensions (Kaufmann et al., 2002).”