Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

By Eran Elinav, Roni Nowarski, Christoph A. Thaiss, Bo Hu, C. Jin, R. Flavell. Nature Reviews. Cancer, 2013

1,903 citations recorded by the source corpus.

Subfields: Immunology, Oncology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/151e403f14ea52460de66fd28aa3a8081b04624b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Y. Belkaid
2. T. Hand

In Oncology

1. Shen Shen
2. Inder M. Verma
3. Yifeng Xia
4. Y. Belkaid
5. T. Hand

Citations in the corpus

• NF-κB, an Active Player in Human Cancers (2014, positive): “Chronic inflammation can lead to genomic instability and genetic mutations that favor tumor initiation and development (21, 22).”
• Current understanding of dysbiosis in disease in human and animal models (2016, background): “Intestinal dysbiosis is believed to contribute to exacerbating chronic inflammation, which is thought to be the leading cause of colitis-associated CRC development.(46) It has been suggested that an increased immune response toward the antigens of the dysbiotic gut microbiota may lead to this chroni”
• Role of the Microbiota in Immunity and inflammation (2014, background): “Notably, IBD and, in particular, CD are associated with the development of colon cancer (Elinav et al., 2013).”
• Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription (2016, methodology): “The intron of the Txs gene and the promoter regions of IL6 (1) and IL1b (4) were used as negative controls.”
• The effects of acute psychological stress on circulating and stimulated inflammatory markers: A systematic review and meta-analysis (2017, background): “cancer, HIV, asthma, and rheumatoid arthritis (Choy, 2012; Deeks et al., 2013; Elinav et al., 2013; Fu et al., 2013; McInnes & Schett, 2011; Naugler & Karin, 2008).”
• The Sleep-Immune Crosstalk in Health and Disease (2019, background): “, HIV, RA), numerous other diseases emerged in the last decades for which mild systemic elevations of inflammatory markers are characteristic, including cardiovascular (481) and metabolic diseases (153), certain forms of chronic pain (23), certain cancers (165), and neurodegenerative diseases (9).”
• Progress in tumor-associated macrophage (TAM)-targeted therapeutics (2017, neutral): “’s excellent review on this topic [35].”