Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds

By E. N. Garza-Treviño, L. Ixtepan-Turrent, Dinesh. K. Singh. Journal of Nanobiotechnology, 2011

693 citations recorded by the source corpus.

The advance in nanotechnology has enabled us to utilize particles in the size of the nanoscale. This has created new therapeutic horizons, and in the case of silver, the currently available data only reveals the surface of the potential benefits and the wide range of applications. Interactions between viral biomolecules and silver nanoparticles suggest that the use of nanosystems may contribute importantly for the enhancement of current prevention of infection and antiviral therapies. Recently, it has been suggested that silver nanoparticles (AgNPs) bind with external membrane of lipid enveloped virus to prevent the infection. Nevertheless, the interaction of AgNPs with viruses is a largely unexplored field. AgNPs has been studied particularly on HIV where it was demonstrated the mechanism of antiviral action of the nanoparticles as well as the inhibition the transmission of HIV-1 infection in human cervix organ culture. This review discusses recent advances in the understanding of the biocidal mechanisms of action of silver Nanoparticles.

Subfields: Materials Chemistry, Obstetrics and Gynecology

View Paper: https://www.semanticscholar.org/paper/149fc45f3afcc5c36312716119be6a63b251ecd5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. M. Rai
2. K. S. Siddiqi
3. Uttam Chand Banerjee
4. R. Rao
5. Amit Mittal
6. Y. Chisti
7. Azamal Husen
8. M. S. Mehata

Citations in the corpus

• Silver Nanoparticles as Potential Antibacterial Agents (2015, background): “considered, in recent years, particularly attractive for the production of a new class of antimicrobials [4,18–25] opening up a completely new way to combat a wide range of bacterial pathogens.”
• A review on biosynthesis of silver nanoparticles and their biocidal properties (2018, background): “Although, several reviews have been published on the fabrication and characterization of silver nanoparticles, very limited reports are available on their green synthesis, biocidal properties and mechanism of action [8, 9, 13, 16, 23].”
• Synthesis of metallic nanoparticles using plant extracts. (2013, background): “…et al., 2011; Arulkumar and Sabesan, 2010; Duran et al., 2007; Jain et al., 2009; Kandasamy et al., 2012; Kim et al., 2007; Krishnaraj et al., 2010; Lara et al., 2011; Patil et al., 2012a,b; Prasad and Elumalai, 2011; Ravindra et al., 2010; Sathishkumar et al., 2009b; Saxena et al., 2011; Seil and…”
• Natural Polymeric Scaffolds in Bone Regeneration (2020, background): “Among antimicrobial agents, silver induces disruption of bacterial cell membranes and inhibits DNA replication, enzymatic activity, and ATP production (Rai et al., 2001; Lara et al., 2011).”
• Antibacterial mechanism of biogenic silver nanoparticles of Lactobacillus acidophilus (2015, background): “[12] The use of silver nanoparticles have found to be effect on the other micro-organism, from usage of L.”