Mitochondrial Dynamics and Metabolic Regulation.

By T. Wai, T. Langer. Trends in endocrinology and metabolism, 2016

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Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity (2017, background): “Mitochondrial function and dynamics in obesity Mitochondria have emerged as important players in the development of a number of metabolic disorders including obesity, type 2 diabetes mellitus, and cardiovascular diseases (Wai and Langer, 2016).”
PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism (2020, background): “contrast, the major proteins involved in mitochondrial fission are dynamin-related protein 1 (DRP1) and fission protein 1 (FIS1) [174].”
Mitochondrial dysfunction and oxidative stress in metabolic disorders - A Step towards mitochondria based therapeutic strategies (2016, background): “Mitochondrial fragmentation occurs in response to nutrient excess and cellular dysfunction escalates the prevalence of obesity, cancer, cardiovascular and neuromuscular disorders [71].”