Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects.
By M. Cleuvers. Toxicology Letters, 2003
940 citations recorded by the source corpus.
Subfields: Analytical Chemistry, Health, Toxicology and Mutagenesis, Pollution
View Paper: https://www.semanticscholar.org/paper/13034bdc28e3c7c909aa67447920127a14fbae12
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In Analytical Chemistry
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Citations in the corpus
- Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. (2007, neutral): “, Cleuvers (2002). US FDA-CDER (1996).”
- Removal of pharmaceuticals during wastewater treatment and environmental risk assessment using hazard indexes. (2010, result): “Some studies, like those performed by Cleuvers (Cleuvers, 2004; Cleuvers, 2003) revealed that a”
- Ecotoxicology of human pharmaceuticals. (2006, background): “Shortterm acute toxicity was analyzed in algae and invertebrates (Webb, 2001; Cleuvers, 2003), phytoplankton was found to react more sensitive [lowest EC50 (96 h) = 14.5 mg/L (Ferrari et al., 2004)] than zooplankton [lowest EC50 (96 h) = 22.43 mg/L (Ferrari et al., 2004)].”
- Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. (2013, background): “Tests with combinations of various pharmaceuticals (carbamazepine, diclofenac, and ibuprofen) revealed stronger effects than expected from the effects measured singly to the target aquatic organism—Daphnia magna (Cleuvers, 2003).”
- Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. (2004, methodology): “For example, an earlier study (Cleuvers, 2003) indicated that the EC50 values of tested NSAIDs obtained using the duckweed Lemna minor were 5- to 10-fold lower than those obtained using the acute Daphnia or algal test.”
- Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment (2017, neutral): “[35]; whereby the antiepileptic drug e carbamazepine and the lipid lowering agent clofibric acid (both belonging to different therapeutic classes) exhibited much stronger effects to Daphnia magna than single compounds at the same concentration [154].”
- Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment--a review. (2012, neutral): “…EC50 ECOSAR 101 Sanderson et al. (2003) 13.8 Daphnia EC50 ECOSAR 111 Sanderson et al. (2003) Algae EC50 ECOSAR 70 Sanderson et al. (2003) Algae EC50 (3 days) 74 Cleuvers (2003) Bacteria EC50 (15 min) 52.2 Kim et al. (2007) Fish EC50 (48 h) 35.4 Kim et al. (2007) Daphnia EC50 (48 h-mortality)…”