Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria.

By Clayton W. Hall, T. Mah. FEMS Microbiology Reviews, 2017

1,443 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/127097eaba6bda228c733e5ff62b8a4b4285ac23

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. K. Gupta
2. M. Mandal
3. Scott A. Beatson
4. David L. Paterson
5. T. Mah
6. M. Rather

In Molecular Medicine

1. K. Gupta
2. M. Mandal
3. David L. Paterson
4. T. Mah
5. M. Rather

Citations in the corpus

• Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance (2020, background): “Such combination varies depending upon aspects such as the bacterial species or strain, the antimicrobial agent, the developmental stage f the biofilm, and the b ofilm growth condition [63].”
• Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action (2019, background): “The resistance of biofilm to antibiotic treatments may be explained by various molecular mechanisms [12].”
• Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies (2021, background): “The factors which contribute towards antibiotic resistance of biofilm include restricted antimicrobial penetration, antibiotic-modifying enzymes in matrix, eDNA, hypoxia, reduced growth, variability in physiology, oxidative stress and amino acid starvation responses, efflux pumps, quorum sensing, pe”
• Antimicrobial Resistance in ESKAPE Pathogens (2020, background): “The reduced antibiotic susceptibility exhibited by biofilm-embedded cells is thought to be multifactorial and can vary according to the species and genetic makeup of the organism(s), the nature of the antimicrobial agent, the developmental stage of the biofilm, and the environmental conditions (118,”
• Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention (2018, background): “gradients that slow the penetration of antibiotics to the core of the biofilm, mediating tolerance [1, 36, 39].”
• Understanding bacterial biofilms: From definition to treatment strategies (2023, background): “Anoxia, nutrient deficiencies, antibiotic modification enzymes, and oxidative stress can also lead to antibiotic resistance in bacterial biofilms (Hall and Mah, 2017).”