A peptide carrier for the delivery of biologically active proteins into mammalian cells

By M. Morris, Julien Depollier, J. Méry, F. Heitz, G. Divita. Nature Biotechnology, 2001

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View Paper: https://www.semanticscholar.org/paper/10894a4434d5dcd3c4c70be428c8f7b71c4821e0

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Citations in the corpus

Cell‐penetrating peptides: 20 years later, where do we stand? (2013, neutral): “In order to get a direct read-out of the peptide entry into cells, methods to detect the biological activ- Table 1 Origin and sequences of some of the studied CPPs. Peptide Origin Sequence Reference Protein-derived Penetratin Antennapedia (43–58) RQIKIWFQNRRMKWKK [6] Tat peptide Tat(48–60) GRKKRRQRR”
Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics (2009, neutral): “, 1997) closely followed by development of Pep-1 for non-covalent cellular delivery of proteins and peptides (Morris et al., 2001).”
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein (2005, background): “Tagged gene products that are cytotoxic or inhibitors of translation might interfere with the subsequent expression of GFP 1–10 OPT in living cells, but this limitation could likely be overcome in mammalian cells by using protein transfection reagent”
Circular Dichroism Techniques: Biomolecular and Nanostructural Analyses‐ A Review (2009, background): “These biological macromolecules, have created a new horizon in biomedical research to obtain most efficient ways to carry substantial cargoes such as peptides (38,39), proteins (40), plasmid DNA (41), oligonucleotides (42), peptide nucleic acids (PNA) (43,44), and even nanoparticles (45) or liposome”
Quantum Dots for Live Cell and In Vivo Imaging (2009, methodology): “The peptide mediated approach employed the amphiphilic peptide Pep-1 (KETWWETWWTEWSQPKKKRKVcystamine), which is part of the cell-penetrating peptide family that has been previously used for delivery of biomolecules and quantum dots into cells [24,109].”
Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses (2009, positive): “(Active Motif) following the manufacturer’s instructions with minor modifications (Kittler et al., 2006; Morris et al., 2001; Payne et al., 2003; Remacle et al., 2005; Sloane and Vartanian, 2007).”