Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells.

By D. Hazuda, P. Felock, M. Witmer, A. Wolfe, K. Stillmock, J. Grobler, Amy S. Espeseth, L. Gabryelski, W. Schleif, C. Blau and 1 more. Science, 2000

1,116 citations recorded by the source corpus.

Subfields: Infectious Diseases, Molecular Biology, Virology

View Paper: https://www.semanticscholar.org/paper/10484e3e6f45731247b03377bdd94e196b9fb823

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In Molecular Biology

1. Trey Ideker
2. Frederic D. Bushman
3. Roded Sharan
4. Rob Knight
5. Anastasia Baryshnikova
6. Donna K. Slonim
7. Tommaso Cai

Citations in the corpus

• A quantitative assay for HIV DNA integration in vivo (2001, result): “We found the ratio of 1-LTR to 2-LTR circles to be roughly 9:1 ( Fig 2 e , lane 8), a conclusion consistent with published studie”
• Global analysis of host-pathogen interactions that regulate early stage HIV-1 replication (2008, methodology): “For control purposes, parallel infections were performed in the presence of an HIV-1 integrase inhibitor (Hazuda et al., 2000).”