Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia.

By Shitij Kapur, R. Zipursky, Corey Jones, G. Remington, S. Houle, C. F.R.C.P.. American Journal of Psychiatry, 2000

1,097 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/0fbe7aba9f67fb0c5ac2e5db7fb943223cdba66f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. McCutcheon
2. J. Stone
3. Oliver D. Howes

In Psychiatry and Mental health

1. R. McCutcheon
2. J. Stone
3. Oliver D. Howes

Citations in the corpus

• Glutamate and dopamine in schizophrenia: an update for the 21st century (2015, background): “, 2010) despite high levels of D2 occupancy (Kapur et al., 2000).”
• A Research Agenda For DSM-V (2002, background): “PET studies have suggested that, across antipsychotic agents, the degree of dopamine type 2 receptor (D2) occupancy relates to clinical response and extrapyramidal signs (Farde 1997; Kapur et al. 2000; Laruelle 2000).”