Cloned pigs produced by nuclear transfer from adult somatic cells

By I. Polejaeva, Shu-Hung Chen, T. Vaught, R. Page, J. Mullins, S. Ball, Yifan Dai, Jeremy T. Boone, S. Walker, D. Ayares and 2 more. Nature, 2000

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Reproductive technologies in farm animals (2005, methodology): “Work in the USA by Polejaeva et al. (2000) led to the birth of a litter of five cloned pigs, by the use of a new NT method in which fertilized zygotes were used as cytoplast recipients.”
Analysis of Genes and Genomes (2004, background): “cows, goats and pigs (Cibelli et al., 1998; Baguisi et al., 1999; Polejaeva et al., 2000), and in more experimentally amenable laboratory animals such as mice (Wakayama et al.”
Safety of Genetically Engineered Foods. Approaches to Assessing Unintended Health Effects (2005, background): “Cloning by nuclear transfer from embryonic blastomeres (Willadsen, 1989; Willadsen and Polge, 1981) or from a differentiated cell of an adult (Kuhholzer and Prather, 2000; Polejaeva et al., 2000; Wilmut et al., 1997) requires that the introduced nucleus be reprogrammed by the cytoplasm of the egg an”
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. (2008, background): “Even though epigenetic reprogramming of a somatic genome to an embryonic state by nuclear transfer or fusion of ES cells with somatic cells has become a widely used procedure in various mammalian species over the last decade (Cowan et al., 2005; Kato et al., 1998; Polejaeva et al., 2000; Tada et al.”