oPOSSUM-3: Advanced Analysis of Regulatory Motif Over-Representation Across Genes or ChIP-Seq Datasets

By Andrew Tae-Jun Kwon, David J. Arenillas, R. W. Hunt, Wyeth W. Wasserman. G3: Genes, Genomes, Genetics, 2012

298 citations recorded by the source corpus.

oPOSSUM-3 is a web-accessible software system for identification of over-represented transcription factor binding sites (TFBS) and TFBS families in either DNA sequences of co-expressed genes or sequences generated from high-throughput methods, such as ChIP-Seq. Validation of the system with known sets of co-regulated genes and published ChIP-Seq data demonstrates the capacity for oPOSSUM-3 to identify mediating transcription factors (TF) for co-regulated genes or co-recovered sequences. oPOSSUM-3 is available at http://opossum.cisreg.ca.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0f64f36368d9e2f2e132fd7fa437edcc8f84f99d

Citations in the corpus

• Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data (2021, unknown): “The oPOSSUM software 58 (version 3.0) was used to detect the motifs of the transcription factor binding sites for the lung cancer signature genes.”