Antiapoptotic roles of ceramide‐synthase‐6‐generated C16‐ceramide via selective regulation of the ATF6/ CHOP arm of ER‐stress‐response pathways

By C. Senkal, S. Ponnusamy, J. Bielawski, Yusuf A. Hannun, B. Ogretmen. 2010

265 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Michal Levy
2. A. Futerman

In Molecular Biology

1. Michal Levy
2. A. Futerman

Citations in the corpus

• Mammalian Ceramide Synthases (2010, background): “Downregulation of CerS6 in HNSCC resulted in the induction of ER stress, while overexpression of CerS6 increased HNSCC tumor development and growth (80).”
• The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection (2019, background): “Such complexes bind the promoters of several genes involved in UPR (such as CHOP, GRP78, XBP1) and induce target-gene transcription (37, 38).”