Storage of Spatial Information by the Maintenance Mechanism of LTP

By E. Pastalkova, P. Serrano, Deana Pinkhasova, Emma J C Wallace, André A. Fenton, T. Sacktor. Science, 2006

866 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0f4d2e444250e08f99f1459955b307e4c3968d9b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

In Molecular Biology

Citations in the corpus

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression (2008, background): “For example PKMf is involved in setting tags during ELTP in the basal dendrite, whereas CaMKII (or MAPK for ELTD) plays a similar role in apical dendrites [30].”
A single standard for memory: the case for reconsolidation (2009, background): “In light of recent findings that, at the postsynaptic level, the molecular substrate of LTM requires continuous phosphorylation by protein kinase Mζ (PKMζ”
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. (2009, background): “Physiological, pharmacological and genetic interventions that alter or occlude LTP are accompanied by impairments in learning and memory maintenance (Morris et al., 2003; Pastalkova et al., 2006).”
The Persistence and Transience of Memory. (2017, background): “Moreover, pharmacological or genetic interventions thattargetedthesesamecascadesinvivo typically produced analogous effects on memory formation (Morris et al., 1986; Pastalkova et al., 2006; Silva et al., 1992; Whitlock et al., 2006) (for an exception, see, for example, Ban-nerman et al., 2006).”
Making memories last: the synaptic tagging and capture hypothesis (2010, background): “, a PRP the activity of which is known to be necessary for LTP and memory maintenanc”
Regulatory mechanisms of AMPA receptors in synaptic plasticity (2007, background): “This plasticity is essential for maintaining memory and learnin”
How can memories last for days, years, or a lifetime? Proposed mechanisms for maintaining synaptic potentiation and memory (2019, background): “1993), inhibition of PKMζ blocked L-LTP as well as 1 d old spatial memory (Serrano et al. 2005; Pastalkova et al. 2006), and blocked memory for instrumental and classical conditioning (Serrano et al.”
Handbook of ion channels (2015, background): “For example, the zeta-inhibitory peptide (Pastalkova et al., 2006) can robustly reverse LTP in wild-type mice and those lacking the kinase, which is its presumed target (PKM-zeta) (Lee et al.”
Dendritic mRNA: transport, translation and function (2007, background): “Constitutive activity of this enzyme is thought to maintain LTP by increasing the number of active postsynaptic AMPA receptor”
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms (2008, background): “…eventually termed LTP, has been the object of intense investigation because it is widely believed that it provides an important key to understanding some of the cellular and molecular mechanisms by which memories are formed (Martin et al, 2000; Pastalkova et al, 2006; Whitlock et al, 2006).”
Translational control of long-lasting synaptic plasticity and memory. (2009, positive): “Remarkably, application of a peptide that blocks PKMz inhibits both L-LTP maintenance and memory storage (Pastalkova et al., 2006; Shema et al., 2007).”