Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

By M. Takasato, Pei Xuan Er, H. Chiu, B. Maier, Gregory J. Baillie, C. Ferguson, Robert G. Parton, E. Wolvetang, Matthias S Roost, S. Lopes and 1 more. Nature, 2016

602 citations recorded by the source corpus.

Subfields: Molecular Biology, Pulmonary and Respiratory Medicine, Urology

View Paper: https://www.semanticscholar.org/paper/0f05ac4b42fe49b70d92508e7f86df85fb848ec1

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In Molecular Biology

In Pulmonary and Respiratory Medicine

In Urology

Citations in the corpus

Modeling Development and Disease with Organoids. (2016, background): “While remarkably complete, further improvements of the protocol will focus on tubular functional maturation, more extensive glomerular vascularization, and the formation of a contiguous collecting ductal tree ‘‘with a single exit path for urine’’ (Takasato et al., 2015).”
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning (2018, methodology): “For example, kidney organoids have been used for toxicity screening in response to cisplatin (Takasato et al., 2015), an organoid model of cystic fibrosis for drug screening has been described (Dekkers et al., 2013) and a high-throughput platform for intestinal stem cell niche co-cultures has been…”