Arousal Dissociates Amygdala and Hippocampal Fear Responses: Evidence from Simultaneous fMRI and Skin Conductance Recording

By L. Williams, Mary L. Phillips, M. Brammer, D. Skerrett, J. Lagopoulos, C. Rennie, H. Bahramali, Gloria Olivieri, A. David, Anthony Peduto and 1 more. NeuroImage, 2001

313 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/0eca74a642dc53e7d2ea4286ec19c1b0650bf7ac

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Citations in the corpus

Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a "default mode" of brain function (2004, background): “In particular, the amygdala exerts an influence on autonomic responses including skin conductance activity (Asahina et al., 2003; LeDoux, 1996; Phelps et al., 2001; Williams et al., 2001).”
Trauma modulates amygdala and medial prefrontal responses to consciously attended fear (2006, methodology): “In the ROI analyses, non-traumatized subjects elicited left amygdala activity in response to fear, consistent with a number of previous neuroimaging studies (e.g., Morris et al., 1996; Williams et al., 2001).”
Differential neural responses to overt and covert presentations of facial expressions of fear and disgust (2000, result): “…(Dimberg et al., 2000) which demonstrated psychophysiological discrimination between two emotional expressions under conditions in which verbal report was at chance; and identical to those which showed greater SCR responses to fear than to neutral expressions (Williams et al., 2001, 2004).”
Association between heart rate variability and fluctuations in resting-state functional connectivity (2012, background): “Moreover, amygdala activity has been linked to the sympathetic skin response during fear (Asahina et al., 2003; Williams et al., 2001), and shows hyperactivity in depression (Drevets, 2001), a disease having a characteristic decrease in HRV. Studies that have directly examined correlations between…”
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. (2007, background): “These regions are activated by emotional conflict (102), track levels of emotional arousal (111), correlate with autonomic activity (112, 113), and respond in anticipation of an aversive event (96), among related functions.”
Cognitive reappraisal of emotion: a meta-analysis of human neuroimaging studies. (2014, background): “Furthermore, prior work shows that amygdala responses track affective intensity, especially for aversive stimuli like those photos used widely in reappraisal studies (Canli et al. 2000; Williams et al. 2001; Anderson et al. 2003; Cunningham et al. 2004; Ochsner et al. 2004, 2009; Phan et al. 2004).”
Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging (2003, background): “First, we did not have an effective way of coding for the arousal levels of various tasks, and in order to make fair comparisons between conditions, such as positive and negative stimuli, the intensity of the elicited responses should be equated, as systematic effects of arousal on brain activation ”
Neuroimaging Support for Discrete Neural Correlates of Basic Emotions: A Voxel-based Meta-analysis (2010, methodology): “…task V (Pictures) S Whalen et al. (1998) fMRI 4m, 4f 25 Viewing facial expressions V (Faces) A F Wicker et al. (2003) fMRI 14m N/A Mood induction O D Williams et al. (2001) fMRI 11m 30 Viewing facial expressions V (Faces) A Williams et al. (2004) fMRI 15m, 7f 27.5 Viewing facial expressions V…”