Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1.

By J. Burger, N. Tsukada, M. Burger, N. Zvaifler, M. Dell'aquila, T. Kipps. Blood, 2000

821 citations recorded by the source corpus.

Subfields: Genetics, Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/0e5680527fbc1a53006422f557c2486ba6828821

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Ralf Küppers
2. D. Calado

In Immunology

1. Ralf Küppers
2. J. Benovic
3. J. Busillo

In Oncology

1. Ralf Küppers
2. J. Benovic
3. J. Busillo
4. D. Calado

Citations in the corpus

• From pathogenesis to treatment of chronic lymphocytic leukaemia (2010, background): “NLCs can develop in vitro from CD14 + monocytes by interaction with CLL cell”
• Regulation of CXCR4 signaling. (2007, background): “For example, the combination of CXCR4 expression and interaction with stromal or nurse-like cells in chronic lymphocytic leukemia [149] and multiple myeloma [150] may account for resistance to spontaneous/drug induced apoptosis and cell adhesion-mediated drug resistance, essentially providing a prot”
• Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease (2003, background): “Moreover, CXCR4 and SDF-1 signaling has been shown to inhibit spontaneous apoptosis in human chronic lymphocytic leukemia B cell”