Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

By J. R. Newman, Sina Ghaemmaghami, Jan Ihmels, David K. Breslow, M. Noble, J. Derisi, Jonathan S. Weissman. Nature, 2006

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Correlation of mRNA and protein in complex biological samples (2009, positive): “Namely the TAP-tag (tandem afﬁnity puriﬁcation) and fusion of cellular proteins with the green ﬂuorescent protein (GFP) lead to global measurements of protein abundance in cells [37,38].”
Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells (2015, background): “The cell cycle is known to have wide-ranging effects on cellular physiology 26,27 and can modulate both differentiation and gene expression profiles 28 ( Fig.”
Stochastic mRNA Synthesis in Mammalian Cells (2006, neutral): “component to the variations in yeast [17,18].”
Cellular heterogeneity: when do differences make a difference? (2010, background): “Cellto-cell differences, for example those due to biochemical noise (Elowitz et al., 2002; Newman et al., 2006; Ozbudak et al., 2002; Raser and O’Shea, 2004), may have no functional significance.”