Cytoplasmic m6A reader YTHDF3 promotes mRNA translation
By Ang Li, Yu-Sheng Chen, X. Ping, Xin Yang, Wen Xiao, Ying Yang, Hui Sun, Qin Zhu, P. Baidya, Xing Wang and 4 more. Cell Research, 2017
713 citations recorded by the source corpus.
Subfields: Electrical and Electronic Engineering, Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/0c82d992c8900d3e692a0018fbfd08c2c4695358
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In Electrical and Electronic Engineering
In Molecular Biology
Citations in the corpus
- A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA (2020, background): “…YTHDF1, YTHDF2, and YTHDF3 (DF1, DF2, and DF3, respectively), each of which have different reported functions: DF1 enhances mRNA translation, DF2 promotes mRNA degradation, and DF3 enhances both translation and degradation (Li et al., 2017; Shi et al., 2017; Wang et al., 2015; Wang et al., 2014a).”
- Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism (2018, background): “They do not bind to m6A directly, but instead, m6A serves as a structural switch to alter the RNA structure, which renders transcripts more accessible for binding by HNRNPC and HNRNPG. Cytoplasmic m6A readers After being processed from precursor transcripts, mature mRNAs containing m6A are further r”
- Methylation multiplicity and its clinical values in cancer (2021, positive): “YTHDF3 could interact with YTHDF1 or YTHDF2 to enhance its ability in enhancing translation and mediating protein decay (Refs 36, 37).”
- Functions of N6-methyladenosine and its role in cancer (2019, background): “YTHDF3 enhances translation and degradation by interacting with YTHDF1 and YTHDF2 [33, 34] He et al.”