Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding.

By B. Keselowsky, D. Collard, Andrés J. García. Biomaterials, 2004

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Surface engineering approaches to micropattern surfaces for cell-based assays. (2006, background): “Besides projected cell shape, it is known that the type of ligand, their accessibility by the cells and their conformation influence the cellular response [81,128].”
Foreign body reaction to biomaterials. (2008, background): “[49] This indicates that differences in downstream integrin signaling account for morphological differences in adherent cells on material surfaces.”