Role of the serrated pathway in colorectal cancer pathogenesis.
By B. Leggett, V. Whitehall. Gastroenterology, 2010
976 citations recorded by the source corpus.
Subfields: Oncology, Pathology and Forensic Medicine, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/09fff9c6fcddec5cbcec76d36fc61947d837b93b
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Citations in the corpus
- Serrated Lesions of the Colorectum: Review and Recommendations From an Expert Panel (2012, background): “TSAs are much less common than SSA/Ps, so there are fewer data on their molecular profile (16, 48).”
- ACG Clinical Guidelines: Colorectal Cancer Screening 2021. (2021, background): “, CpG island methylator phenotype), and a presumed more rapid progression to CRC; these lesions are also more prevalent in the proximal colon, a location where we recognize colonoscopy to be less protective for CRC compared with the distal colon (150,184,185).”
- Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. (2012, neutral): “23 Concerns about interval cancer may impact physician behavior with regard to surveillance intervals and may contribute to early repeat examinations in some cases.”
- Microsatellite Instability as a Biomarker for PD-1 Blockade (2016, background): “Whereas microsatellite stable (MSS) cancers tend to arise from adenomatous polyps, distributed anywhere in the colon,MSImalignancies tend to arise from sessile serrated adenomas in the proximal colon (38).”
- Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy (2012, neutral): “9% (39,440) underwent two screenings; in 28.”
- Deep Learning for Classification of Colorectal Polyps on Whole-slide Images (2017, background): “e polyps. As an example, sessile serrated polyps can potentially develop more aggressively into colorectal cancer compared to other colorectal polyps, because of the serrated pathway in tumorigenesis [23]. The serrated pathway is associated with mutations in the BRAF or KRAS oncogenes, and CpG islan”