Self-organization mechanism in a bone-like hydroxyapatite/collagen nanocomposite synthesized in vitro and its biological reaction in vivo.

By M. Kikuchi, S. Itoh, S. Ichinose, K. Shinomiya, J. Tanaka. Biomaterials, 2001

800 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/0962241e2ba502fa0c7b7276ca067f5277549e65

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In Biomaterials

1. Shaylin Shadanbaz
2. H. Ehrlich
3. H. Rashid
4. Z. Sheikh
5. V. Verma
6. G. Dias
7. D. Wahl
8. Zohaib Khurshid

In Biomedical Engineering

1. D. Wahl
2. H. Rashid
3. Z. Sheikh
4. V. Verma
5. Zohaib Khurshid
6. J. Czernuszka
7. M. Glogauer
8. S. Najeeb

Citations in the corpus

• Developing bioactive composite materials for tissue replacement. (2003, background): “A combination of these two methods has produced collagen-based composites containing bone-like apatite [39].”
• Biodegradable Materials for Bone Repair and Tissue Engineering Applications (2015, background): “Hence, composites produced using calcium phosphates and collagens are considered as the most biomimetic system for osseous replacement and regenerative applications [192–196].”
• Calcium phosphate coatings on magnesium alloys for biomedical applications: a review. (2012, positive): “minipigs, where bone generation was apparent at 5 and 9 weeks [133], and in beagles at 8 and 12 weeks [134].”
• Collagen-hydroxyapatite composites for hard tissue repair. (2006, methodology): “Undenatured collagen films can be obtained from an acidic collagen suspension by air dehydration at different temperatures (4-37°C) or by applying cold isostatic pressure (200MPa) for 15h (Kikuchi et al., 2001).”
• Chitin and collagen as universal and alternative templates in biomineralization (2010, background): “…example, Cui et al. (2007) suggested that the nucleation sites of HAP crystals on collagen fibres could be through the binding of calcium ions on the negatively charged carboxylate groups of collagen and be one of the key factors for the first-step nucleation of HAP crystals (Kikuchi et al. 2001).”
• Characterization of Bone and Bone-Based Graft Materials Using FTIR Spectroscopy (2012, background): “…and disease transmission. www.intechopen.com Characterization of Bone and Bone-Based Graft Materials Using FTIR Spectroscopy 329 Currently, the most common alternatives to bone-based grafts are synthetic biomaterials (often composites made of Ca/P ceramics and polymers) (Kikuchi et al., 2001).”
• Bone structure and formation: A new perspective (2007, background): “There has been partial success at mimicking some of the nanostructural features of bone by performing the crystallization in situ during fibrillogenesis, during which some crystals appear to nucleate at the hole zones [99], and in some cases yield similar electron diffraction patterns indicating uni”