Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

By Kevin C. Wang, V. Koprivica, Jieun A. Kim, Rajeev Sivasankaran, Yong Guo, Rachel L. Neve, Zhigang He. Nature, 2002

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Rho Kinase Inhibition Enhances Axonal Regeneration in the Injured CNS (2003, background): “…glycoprotein (MAG) (McKerracher et al., 1994; Mukhopadhyay et al., 1994; Liu et al., 2002), chondroitin sulfate proteoglycans (Niederost et al., 1999), oligodendrocyte myelin glycoprotein (Wang et al., 2002), and Nogo (Chen et al., 2000; GrandPre et al., 2000; Prinjha et al., 2000).”
Neural tissue engineering: strategies for repair and regeneration. (2003, background): “other growth inhibitors found in myelin, myelin-associated glycoprotein (MAG) (261), and oligodendrocyte-associated glycoprotein (OMgp) (262).”
From carbohydrate leads to glycomimetic drugs (2009, background): “To date, three major inhibitor proteins have been identified: reticulon 4 (RTn4; also known as nogo A) 76 , myelin oligodendrocyte glycoprotein (MOG) 77 and MAG 78 .”
Neurotrophins and their receptors: A convergence point for many signalling pathways (2003, background): “Unexpectedly, there are other ligands for this Nogo receptor, including oligodendrocyte myelin glycoprotei”
The role of the Rho GTPases in neuronal development. (2005, background): “Primary neurons from p75NTR knockout mice are no longer responsive to CNS myelin, Nogo-66, OMgp, and MAG (Wang et al. 2002a; Yamashita et al. 2002), and an antibody against p75NTR abolishes MAG-induced repulsive turning of Xenopus axonal growth cones and calcium elevation (S.T. Wong et al. 2002).”